What is ldl p

When cholesterol and particle number tests disagree, your risk for a cardiovascular event is more accurately assessed using your particle number, rather than cholesterol. Achieving a low particle number LDL-P significantly improves your risk of not suffering future cardiovascular events and brings down your overall cost of healthcare. The higher the scores for a longer time, increases your risk. Here are actions you may consider taking under the care of a licensed physician in your area:.

However, they are also less easily available in most geographies as they are a bit more labor intensive than a CAC score. Clinical utilization of lipoprotein subfractions. Therapeutic Lipidology. Totowa: Humana Press; Low-density lipoproteins cause atherosclerotic cardiovascular disease. Evidence from genetic, epidemiologic, and clinical studies.

Eur Heart J ; Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel.

Eur Heart J Effect of moderate hypertriglyceridemia on the relation of plasma total and LDL apo B levels. Note: Result turn around times are an estimate and are not guaranteed. Category: Heart Health. Continue Shopping View Cart and Checkout 0. LDL P. Sample Report. Requirements: This test requires fasting for hours prior to specimen collection. View more details. This test is not available at Quest. Popular Related Products. Lipid Panel. More Info. NMR LipoProfile. Ultimate Heart Health Panel.

Other Heart Health Tests Aldosterone Renin Ratio. Aldosterone, Urine Hour. Angiotensin Converting Enzyme. Apolipoprotein A1.

Apolipoprotein Assessment Ratio. Apolipoprotein B. Biometrics Health Screening. My diet tends toward high carb and my execise level is on the low end. Not sure of the best course of action in this situation. Maybe someone could comment on this general situation.

Looking at your lipid numbers there is a possibility that you have what is called familial combined hyperlipidemia. My suggestion is that you seek a specialist, either a cardiologist or a lipidologist.

Have you done that? My NP still wants me to start statin therapy which scares me. I want to keep trying to lose weight. Your lipid profile is not that bad really and does by itself not support statin therapy, considering that we are talking primary prevention. I agree with you that you should continue trying to lose weight. I think a Mediterranean type diet including exercise is definitively a good option in your situation. This will hopefully help lowering your TG.

Indeed, a low carb version of the Mediterranean diet might be something to look at as well. Story: obese most of my adult life; low carb 2. In mild ketosis much of the time, with periodic breaks with added carbs. Also LP a is very high Where do I look for what this means? Is the risk real? Can it be managed without drugs? It almost feels as if this is two problems, not one. Or the risk factors have not been vetted against my scenario.

Considering your weight and diabetes I would suspect you fulfill criteria for the metabolic syndrome. So it is a bit surprising that your LP-IR score is this low. Actually, you can often get confused with all these numbers. Maybe you should look at your lifestyle in general and see what you can do to reduce your risk. The saturated fats will not help you lower LDL-C. I wonder whether switching to a more of a Mediterranean type diet, using more monounsaturated and omega 3 fats, might help you.

It is a good diet for type-2 diabetes and for weight loss. I am worried due to my weight and LDL-P ratings. Should I be and what should I do. My overal Cholesterol has dropped from when I was 28 to this number now that I am I take Lipator 10mg. Considering that you are overweight, weight loss probably reduces your risk.

Cutting down on sugar and refined carbohydrates often helps lowering LDL-P. Thank you for your thoughts. I believe the IR is under control because of 2. I control post prandial glucose rigorously by eating very few if any carbs. Obviously, there are some things we do not understand yet.

Thanks again for considering. Thank you for you very enlightening blog. In Dr. A body with low inflammation, there should be no arterial damage from glycation. Therefore, the LDL-P has no injury to deposit its load of cholesterol for repair, thus no plaque. Hi Peter. Sorry for my late response. I read Dr.

Patels article. Very interesting. I think you are right. We often tend to treat laboratory values. We have to see the whole picture. We know that inflammation plays a role in atherosclerosis, and we know that lipids do as well. There are ongoing clinical trials on the effects of anti-inflammatory drugs in patients with heart disease. They might actually provide some answers to the role of inflammation in cardiovascular disease.

It is a pro-inflammatory state. Lowering lipids is important and will affect risk. Affecting other risk factors is important as well, and will help reduce risk of heart disease. The importance of lipids as a risk factor becomes less if you can reduce the role of other risk factors. I am a 42 year old female. Good morning Doc. There are a lot of FLAGs on the results, so trying to decide if I should see a cardiologist or regular doctor.

Your thoughts?? She had a stent implanted and no other occurances. Also exercising at least 5 days a week for 30 min.

Here are my numbers:. LDL Size Thank you for your post and for sharing your numbers. However, I understand that some studies have shown that statins may be effective for prevention when the KIF6 polymorphism is present, while this was not confirmed by rosuvastatin in the JUPITER trial.

Carbohydrate restriction, Mediterranean diet and Omega -3 fatty acids may all be helpful. Avoiding sugars, eating healthy natural fats and exercising are probably helpful. I believe you are on the right track by eating healthier; steel cut oatmeal, fish, etc.

Good luck. Would love you to get your thoughts on my numbers. I started going to a cardiologist about a year go as I was having some random chest pains, he attributed this to stress after a battery of tests — EKG, Stress test, Echo, Echo stress, CIMT but I did discover I had a leaky aortic heart value, mild to moderate leak.

During my visits there I got my blood work done a few times and was shocked to learn my LDL-P was ! Since then, 8 months ago, I have dropped 20 lbs, starting running 4 times a week and removed all sugary drinks from my diet. During my last visit, my Dr mentioned going on a statin, would love to get your thoughts on this.

LP-a 13 hs-CRP 0. Hi Mike. Well done, congratulations. Total cholesterol, triglycerides, HDL-C all quite acceptable. ApoB is fine and so is Lp a. HsCRP is ok. No diabetes. Considering the absence of other risk factors such as family history, hypertension and smoking, the risk of cardiovascular disease in the near future should be quite low.

She is focused on the LDL-P number and says none of the other numbers matter. No one told me. Should I continue very low carbing? Should I take the statin? My most recent A1C is 5. Thank you for any clarity you can provide. Total cholesterol is a bit high, so is LDL-choleseterol.

However, when considering risk and potential benefits of statin therapy you have to look at other risk factors as well, such as family history, smoking and blood pressure. You will also have to keep in mind potential side effects of such therapy.

Some specialists have claimed that the efficacy of statin therapy in primary prevention may be less in women than men. Barbara Roberts has written a wonderful book The truth about statins where she discusses the pros and cons of statin therapy and suggests that such treatment may be less influential in women than in men.

I agree with your doctor that there are studies indicating that statin therapy may lower your risk of hart attack and stroke.

The important thing however, is that you understand the magnitude of benefit, in relation to the risk of side effects. That is something you should be able to discuss with your doctor.

It might be, if you are overweight or have signs of the metabolic syndrome. If we look at cardiovascular risk in general, a Mediterranean type diet may be helpful. Any physician pushing this class of drugs for women is ignoring the evidence, or lack thereof. At the least, you should ask for a coronary calcium test to get a picture of the degree of blockage if any in one of your major blood vessels. In a conversation with Dr. Tom Dayspring, a prominent U.

Dayspring admitted that there are no good studies of very-low-carbers, and that a different standard might be appropriate.

Hello Doc. Thank you for all this information and for helping all of us. His father had a major stroke at age 55 and now lives in an assisted care facility.

This has obviously been a difficult thing for his family and so this whole cholesterol issue is quite emotional and scarey for my hiusband. We started with low carb but have increased them in the last few months.

It seems his LDL is increasing rapidlyof late. My limited understanding is that apoB predicts particle do you know what this apoB number would translate to in LDL-P? We drink freshly pressed green juice most mornings spinach, carrot parsley ginger apple lemon.

Sorry for the excessively long message. Just frustrated after putting so much care and effort into making good choices and getting results like this. Any feedback on which direction to turn would be helpful. Thank you so much for your time. Hi Tami. Thanks for your post. Although Paleo and low carb diets have many health benefits they are certainly not the best diets to lower total cholesterol and LDL-cholesterol. In a normal weight person with LDL-levels this high, I would rather go for a Mediterranean type diet as you suggest, as it might lower cardiovascular risk.

If he had, you would certainly have to wonder whether he has familial hypercholesterolemia FH. Maybe he should discuss with his doctor about genetic testing for FH.

Lipid guidelines usually recommend statins if LDL-C is above 4. Thank you for your reply. I really appreciate your feedback. There is no family history of coronary artery disease, just the stroke as I mentioned above. We will still rule out FH. The interesting thing about this situation is that for the first year plus of paleo his cholesterol rose only modestly-this past reading increased from an LDL of 4. Is it possible that there is an explanation or cause that should be at least looked for and addressed before artificially lowering the number?

I understand your concern Tami. Fish oils and omega-3 supplements may be helpful as well. Then he could have his lipid numbers reevaluated in six months. Sometimes hypothyroidism low thyroid function causes elevation of LDL-cholesterol, but I assume this has been ruled out already. Anyway, wondering what diet I could do to lower LDL-p..? I have Hoshimotos, could that make my LDL-p so high. Your triglycerides are high as well.

However, to your benefit HDL-C is high as well. There is no particular diet that lowers LDL-P. A Mediterranean type diet may be helpful. Omega-3 may help as well. Reducing carbs may help. The Hashimotos might possibly explain the elevated hcCRP. I am 60 years old. I consider myself to be in great shape. Most people think I am My numbers are:. Lots of other numbers — not sure what you would want. My doctor wants me to take a baby aspirin. My last doctor said to quit the baby aspirin.

What do you think? What else can I do to avoid problems? Thank you so much. Just found this site and it is so informative. I hope you understand that it is very difficult and irresponsible of me give individual recommendations. Therefore I can only answer you in very general terms. Your lifestyle appears to be healthy. Avoiding refined sugars and processed meat will probably help. Lots of fish, vegetable, fruit, fiber and seeds is not a bad idea. Thank you so much for responding.

I appreciate your suggestions and will work on them. God bless. Thank you for this information. I have recently been put on statin and niacin therapy and would like to ask your opinion. Total — ApoB After my test 3 months prior I was put on niacin and baby aspirin once per day.

Now my doctor has added pravastatin. I eat an anti inflammatory diet, mostly gluten and dairy free. I have a glass of red wine every evening while cooking dinner.

After reading my post I want to make sure it makes sense. The first numbers after the type of protein, etc are the most recent results taken in February. The second number is from the test taken in December after the stroke. Sorry to hear about your stroke.

I guess the main reason you are being treated with statins is the stroke, rather than the lipid numbers per se. In my practice we more or less give statins to all persons who suffer ischemic stroke.

However, niacin is much less used in Europe than in the US. If your lifestyle is healthy as you suggest, including exercise and healthy food choices, I guess there is probably not much more you can do.

I assume you are taking aspirin or some other blood thinner as well. I am on coumadin due to the PEs and am considering adding mg niacin and maybe mg Omega 3. And is it common for Lipo a to go from 8 to 31 in 5 weeks? Thanks in advance. It is always difficult for me and probably irresponsible to give advice in individual cases so I will try to respond in general terms.

I often recommend Omega-3 in similar situations. Lipo a is usually stable and not very much affected by diet. Reducing intake of saturated fats may be helpful to get your LDL-C down a bit more. Avoiding refined sugars and limiting simple carbs may help lowering LDL-P. CRP is not elevated which is good. I am a 58 year old with a BMI of 29 and a family history of chd.

I have cleaned up my diet and take fish oil, aspirin, metoprolol and atorvastatin 40mg. Can you give me any advice on reducing my risk? I think your blood work is acceptable.

LDL-C is low, probably due to the statin therapy. You are a bit overweight. Reducing refined sugars and simple carbs may help you lose weight and lower LDL-P further, particle size might also be positively affected. Had let my diet slip and hba1c had crept up to 7.

Went on Paleo diet and have brought that down to 5. Take IU of Vit D to keep levels around My family doctor wants me to go on low-dose statin, primarily due to my diabetes and RA. All of the comments and your responses have been fascinating and quite illuminating. I appreciate the effort you put into this! The statin issue is always a bit difficult in primary prevention. It would be irresponsible of me to advise you on whether to take a statin drug or not.

Your LDL-C is not that bad really, although some doctors might recommend statins because of your diabetes. However, you seem to be controlling your diabetes rather well with diet. Particle testing might help or even measuring hsCRP, though the latter might be elevated due to your RA. Am awaiting particle testing results. Recent 4 weeks ago homocysteine level was Any thoughts on that or how to lower it?

Generally, I have been taking mcg of folic acid per day, but I have ordered a better form 5-Methyl-tetrahydrofolate and will start taking it. I had read that one should shoot for a reading of 6 or below. Not sure if I can get to that point or not.

Both my family doc and my endocrinologist want me to take a low dose statin, but I think that is primarily because that is what they are taught if you have RA and diabetes,then you at risk and thus are a fool not to take this. I also eat quite a bit of coconut products — I wonder if that would contribute to a higher LDL?

I am due for a blood draw on Friday and have talked to my doctor about getting an LDL-P test in addition to the normal cholesterol level checks he does based on some research I have done. He a general practitioner knew nothing of the test but with my explanation he agreed that it might be a good idea. The doc is working with me on reducing the BP meds and monitoring my BP readings. Do you see any other test that I should ask for, or do you think that if the LDL-P number is low and the rest come back in normal range that I can feel comfortable that as long as I continue to eat this way and exercise that my risk is low?

I do have family history of heart disease. Thanks, Janet. I guess I should add…. I started at lbs. So, I went ahead and had my doc get the LipoProfile test. Here are my numbers from the LipoProfile. I had a my carotid artery cleaned out recently. They also did a nuclear stress test which was fine.

I am on 20g of Crestor. Crestor effects muscles when exersising and when I added Zetia forget it, could hardly walk. Is bile seq. What about a fibrate? In addition I had low thyroid, but it is normal now since taking Armour Thyroid.

I am watching my diet and exercising, but would like to know what vitamins would help. A friend suggested fish oil tablets. I just got my blood test results and am pretty upset that my LDL-P came up unsually high. I try to exercise once or twice a week.

Am eating most organic foods at home but not so when I eat at restaurants. I avoid all fast foods though. I have been taking krill oil for the past year or so. Was told that it was more effective than fish oil. I am very much against taking any kind of statin. Well, I got my NMR back today. I have diabetes c-peptide score.

HS-crp is. Last HBA1c was 5. Liver enzymes all good. I have been on a low -carb Paleo diet for last 8 months or so. No grains. Mostly wild fish, veggies, salads, nuts, chicken, grass-fed beef. Do use coconut butter in morning smoothies along with MCT oil, avocados,etc.

Usually restrict my nuts to macadamia nuts low omega 6 , on rare occasions almonds or pecans. Take grams of Barleans concentrated fish oil daily. It seems that my total cholesterol has risen as has my calculated LDL-C was around previously.

HDL continues to climb since being on Paleo. Not sure what she will decide now. I assume it must be this low because of how I'm controlling it by diet? I'm 5'10, pounds, so not overweight, and my blood pressure is excellent every time it's checked. Not sure what to make of this. Just got labs back. Hdl p low. What exactly do these results mean? How can I get the numbers in range? Any natural remedies that might work? These factors play a role when assessing risk. HDL-C is ok, at least if you are a man.

I suggest you analyze your current eating habits and see where you can improve. My BMI is 21 and no other health risk. I was doing crossfit religiously for 10 months then got side tracked with a long vacation and personal stuff. Anyways I got my results from my nmr as follows:. Ldl-p Ldl-c Tc. So I ordered it online myself. Can you enlighten me some on what you think of them please? Hi there! Just picked them up…everything is not fine bc several lines of results were highlighted for being flagged for being out of range.

Could you tell me if I should find a dr to follow up with on those results or just wait until next years physical? The most important thing for you is to reconsider your diet and lifestyle in general. It should measure between A small, temporary increase can occur during illness or dehydration; the numbers usually return to normal during recovery, but you should have it rechecked soon. Doc, I would appreciate your opinion on my lipid profile. I have always been borderline and the docs have wanted me on statins but I have resisted total, LDL.

Then my numbers spiked a few months ago. After that, I went on low sat fat diet no red meat, no animal dairy for 3 months, and my numbers are only marginally better, but the full profile paints a bleak picture see below. We are like, what the heck? We might as well eat all the red meat we want.

Nurse practitioner wants to put me on the strongest dose of the strongest statin Crestor. That scares me more than my lipid profile.

I am 52 years old. Height 6 feet, weight my Grandpa's nickname was "skinny". No history of heart disease in family, but Dad has high numbers but not as bad as mine. Fancy scale puts BMI at Eat fish. Flax seed-chia-spinach leaf-protein powder-spirulina-blueberry shake for breakfast. I watch my carbs no ice cream, minimize sugary snacks, no sugary drinks-unless you count beer and wine. Don't know what else I could do. You definitively seem to be doing everything right in terms of diet and lifestyle.

To a large part our lipids are genetically determined. However, to your benefit, there is no family history of heart disease. So, the question remains on whether to take a statin or not. Remember that most people tolerate statins very well. However, there is 9 percent increased risk of diabetes with these drugs.

Discuss with your doctor the possible benefits and the possible disadvantages of statin therapy. The question is always whether the assumed benefits outweigh the risks. Thanks for your response. What struck me about your response is that you made no mention of inflammation and my low CRP number. I guess what I am driving at is this: If inflammation is and stays low, can a person ignore lipid levels and stay off of statins?

I have slight high blood pressure and taking Lisinopril 5 mg one a day, Simvastatin 40 mg one a day, Metoprolol Er 50mg one a day, and an aspring 81 mg one a day. This is under control and have not had a problem since. I like to know what you think of my latest lab report with my condition I have mentioned above.

I have never smoke, exercise 5 times a week, and drink a glass of wine with dinner. I think your numbers are quite good indeed. The effect of simvastatin is best reflected in your relatively low LDL-C. However, if you have coronary artery disease you might want to see LDL-C lower than In that case atorvastatin 40 mg is more effective than simvastatin 40 mg.

You could discuss that with your doctor. I did as you said and ask my Cardiologist to switch to atorvastatin 40 mg. My results came back and my LDL-C is This is a great improvement. Thank you very much for your recommendation!!! Thank you for your response. Great news! I will talk to my cardiologist on my December appointment about atorvastatin.

I just had extensive lipid panels done and never had the LDL-P done until these labs, and shocked at the high ….

What about homocysteine, no one mentions this.. Many studies indicate that there is a positive correlation between blood cholesterol and survival in your age group, meaning that those with higher cholesterol have a better survival than those with low levels. Your family history is also benign considering your parents longevity. Nonetheless, healthy food choices are important for you. I agree with you on the processed food, try to avoid that as well as added or refined sugar.

Regular walking is helpful and omega-3 supplement is probably not a a bad idea. I am a 55 year old female, with a BMI of I exercise regularly and have never smoked.

The results of my recent blood work showed no thyroid or blood sugar problems. Due to my LDL number and an overall cholesterol number of , my doctor ordered a carotid artery scan which revealed minimal plaque. He wants to put me on a statin.