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Uses of methylsulfonylmethane. Medically reviewed by Alan Carter, Pharm. Osteoarthritis and joint pain Recovery after exercise Allergies Ulcers Rosacea How to take Risks and side effects Summary We include products we think are useful for our readers. Treating osteoarthritis and joint pain. Share on Pinterest Studies suggest that MSM supplements may help treat osteoarthritis and joint pain. Promoting recovery after exercise. Treating allergies. Preventing or treating ulcers. Rosacea and inflammation of the skin.
How to take MSM for health benefits. Share on Pinterest MSM is also available in powder form. Potential risks and side effects of MSM.
Latest news Could 'cupping' technique boost vaccine delivery? Scientists identify new cause of vascular injury in type 2 diabetes. Adolescent depression: Could school screening help? Related Coverage. Is tricalcium phosphate bad for your health? Medically reviewed by Lindsay Slowiczek, PharmD. Are melatonin and alcohol safe to mix? It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity. Sulfur compounds such as MSM play important roles in the health of your immune system For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity.
It may also help increase levels of this important compound. Having adequate levels of glutathione is crucial for the overall health and function of your immune system A test-tube study showed that MSM effectively restored glutathione levels and reduced inflammatory markers in mouse cells that had been weakened with HIV proteins MSM may help boost your immune system by reducing inflammation and increasing glutathione levels.
It contains high levels of the sulfur-containing amino acid cysteine. MSM may be beneficial for skin health by acting as a sulfur donor to keratin. This, in turn, can help strengthen this important protein. MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging like wrinkles It may even reduce symptoms of problematic skin conditions such as rosacea, which can cause redness, irritation and inflammation of the skin.
One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin color in people with rosacea MSM may improve skin health by strengthening keratin and reducing inflammation. It could even help reduce symptoms of certain skin conditions, as well. One of the newest areas of research involving MSM is studying its effectiveness in fighting cancer cells. Although the research is limited, the results have been promising so far.
Several test-tube studies have shown that MSM inhibits the growth of stomach, esophageal, liver, colon, skin and bladder cancer cells 23 , 24 , 25 , 26 , It seems to do this by damaging cancer cell DNA and stimulating cancer cell death MSM also appears to prevent the spread of cancer cells, also known as metastasis A study in mice with liver cancer showed that those injected with MSM had fewer tumors, smaller tumor size and less liver damage than those who did not receive the treatment Another mouse study demonstrated that MSM inhibited the growth of human breast cancer cells Although these results are encouraging, more research is needed to determine the safety and efficacy of using MSM in cancer treatment.
Research has shown that MSM exhibits cancer-fighting properties in test-tube and animal studies, but more research is needed. Numerous toxicity studies have been done to assess the safety of MSM and doses up to 4, However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhea.
When applied to the skin, it may also cause mild skin or eye irritation 33 , Additionally, there is concern over mixing MSM with alcohol since other sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages Using MSM supplements is tied to better immune function, accelerated healing and reduced pain because it helps counteract certain byproducts like lactic acid that contribute to the feeling of soreness, inflexibility, pain and stiffness.
In addition, a study in The Journal of Sports Medicine and Physical Fitness , in which it was found that only 10 days of MSM supplementation helped decrease muscle damage via its effect on antioxidant capacity. How does MSM stop muscle pain and damage? It comes back to the role of sulfur in the body, which is largely stored inside tissues that make up our muscles and joints.
It helps repair the rigid fibrous tissue cells in our muscles that become broken down during exercise, therefore helping prevent them from swelling for prolong periods of time. The result is less time needed for recovery, plus reduced pressure, soreness and cramps.
Struggling with thinning hair or balding as you get older? Good news: MSM has been shown to help boost both collagen and keratin levels, two nutrients we absolutely need to form new hair strands and also rebuild strong nails and skin cells. MSM works similarly, since it boosts our ability to heal and bounce back from exercise, stressful events, injuries and even surgeries. Taking it before exercising, such as running, seems to reduce muscle damage and other markers of stress. It can also lessen fatigue felt after exercise and stressful events and support an upbeat mood, energy levels and normal digestion.
Because studies show it can help to reduce inflammation and decrease the release of cytokines and prostaglandins, this supplement can be useful for managing allergic reactions. One study published in the Journal of Alternative and Complementary Medicine found that it can help to reduce symptoms of allergic rhinitis, which can include itching, congestion, shortness of breath, sneezing and coughing.
The principal dietary sources of sulfur are the amino acids called methionine and cysteine. Studies show these are not always consumed in adequate amounts to meet sulfur requirements. In humans and animals, too , pure MSM is naturally found in the adrenal cortex, which is a part of our hormonal system that helps regulate our response to stressors.
MSM essentially makes cells more permeable, releasing certain built-up minerals that can cause problems like calcium, for example , heavy metals, waste and toxins, while also helping usher in nutrients and water.
This helps keep us hydrated and lowers inflammation, which is the root of most diseases. How much MSM do you need or should you use? Usually, milligrams of MSM, taken two to three times daily , is the starting dose recommended for treating osteoarthritis. For example, one study mentioned above gave participants 1, milligrams daily for 12 weeks.
Other reports show that up to three to six grams of MSM daily divided into three doses normally seems to be safe and well-tolerated. MSM can also reduce exercise-related muscle damage, especially when taken before strenuous resistance or endurance exercises, the review states.
This is believed to be due to its antioxidant effects. MSM may increase your sensitivity to alcohol, according to anecdotal evidence.
Some other sulfur-containing molecules are used to combat alcoholism due to severe side effects from the combination. However, researchers haven't yet specifically explored MSM's relationship with alcohol.
Until more is known, it's best to be cautious with alcohol while you're taking MSM. Be sure to inform your healthcare provider that you are going to take MSM. Interactions between MSM and other prescription medications, non-prescription medications, dietary supplements, or herbal remedies are possible but unknown.
If you are going to buy MSM, it is important to buy from a reputable manufacturer or vendor. It is important to select a quality brand. Different brands may vary in the amount of active ingredient they contain. The Arthritis Foundation recommends a dosage of 1, to 3, mg a day. Note any side effects and notify your healthcare provider.
After starting MSM, allow a reasonable amount of time to notice any benefits. If, after a certain time period, you do not notice any benefit, decide along with your practitioner if you should discontinue MSM. MSM, methylsulfonylmethane, is a supplement that can ease pain and inflammation.
It is marketed as a treatment for arthritis, osteoarthritis, gout, and exercise-related muscle pain. It is unclear whether MSM affects gut health. Some alternative health publications suggest MSM may treat leaky gut syndrome, but there are no scientific studies to back this claim. In addition, taking MSM may cause stomach upset or diarrhea. MSM is used as a pain reliever, but it does not affect the brain or make you disoriented in the way opioid pain relievers can. MSM crosses the blood-brain barrier, but its effects on the brain are unknown.
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